Old English Mastiff

FCI Groep: 2

Bij dit ras voorkomende, erfelijke aandoeningen:Uitleg

	Ernst		Behandel- baarheid		Preva- lentie		Score
Heupdysplasiescore=8	(  1.0	+	1.0   )	x	4    =		8
Progressieve retina atrofiescore=8	(  2.0	+	2.0   )	x	2    =		8
Pulmonalis Stenosescore=8	(  1.0	+	1.0   )	x	4    =		8
Retina Dysplasiescore=6	(  1.0	+	2.0   )	x	2    =		6
Elleboogdysplasiescore=5	(  1.5	+	1.0   )	x	2    =		5
Persisterende Pupillaire Membranenscore=5	(  0.5	+	2.0   )	x	2    =		5
Entropionscore=4	(  1.5	+	0.5   )	x	2    =		4
Exposure Keratopathie Syndroomscore=4	(  1.5	+	0.5   )	x	2    =		4
Ectropionscore=2	(  1.0	+	0.0   )	x	2    =		2
Cataractscore=1	(  0.5	+	0.0   )	x	2    =		1
Artritisscore=0	(  2.0	+	0.0   )	x	0    =		0
Cherry Eyescore=0	(  1.0	+	0.0   )	x	0    =		0
Epilepsiescore=0	(  1.5	+	1.0   )	x	0    =		0
Mitralisklepdysplasiescore=0	(  1.0	+	2.0   )	x	0    =		0
Osteosarcoomscore=0	(  2.0	+	2.0   )	x	0    =		0
Patella Luxatie score=0	(  1.0	+	0.0   )	x	0    =		0
Primaire Hypothyreoïdiescore=0	(  1.0	+	0.0   )	x	0    =		0
Spondylosescore=0	(  1.0	+	2.0   )	x	0    =		0
Tricuspidalis Dysplasiescore=0	(  1.0	+	1.5   )	x	0    =		0
Totaal score							51

Bronnen:

• Crook A et al. 2011. Canine Inherited Disorders Database (CIDD). http://ic.upei.ca/cidd/
• Narojek, T. en Fiszdon, K. (2008) Canine elbow dysplasia in different breeds. Genetics Volume: 52, Pages: 169-173
• Orthopedic Foundation for Animals (2011) Hip Dysplasia Statistics. Breeds having at least 100 evaluations January 1974 through December 2010. Columbia, Missouri: OFFA. www.offa.org
• Roberts , T. en McGreevy, P.D. (2010) Selection for breed-specific longbodied phenotypes is associated with increased expression of canine hip dysplasia. The Veterinary Journal 183 (2010) 266-272
• Comhaire FH, Snaps F. (2008) Comparison of two canine registry databases on the prevalence of hip dysplasia by breed and the relationship of dysplasia with body weight and height. Am J Vet Res. 2008 Mar;69(3):330-3.
• Comhaire FH, Schoonjans FA.Canine hip dyslasia: the significance of the Norberg angle for healthy breeding. J Small Anim Pract. 2011 Oct;52(10):536-42.
• LICG (2011) Erfelijke aandoeningen bij honden. Utrecht: Universiteit Utrecht
• Orthopedic Foundation for Animals (2011) Elbow Dysplasia Statistics. Breeds having at least 100 evaluations January 1974 through December 2010. Columbia, Missouri: OFFA. www.offa.org
• Sargan, D. (2004) IDID: inherited diseases in dogs: web-based information for canine inherited disease genetics. Mamm Genome. 2004 Jun;15(6):503-6 Cambridge: University of Cambridge. http://www.vet.cam.ac.uk/idid/
• Peelman, L.J. (2009) Erfelijke afwijkingen bij de hond. Bilthoven: Euroscience
• Clements DN, Fitzpatrick N, Carter SD, Day PJ. (2007) Cartilage gene expression correlates with radiographic severity of canine elbow osteoarthritis. Vet J. 2007 Oct 13;
• Orthopedic Foundation for Animals (2011) Patellar Luxation Statistics. Breeds having at least 100 evaluations January 1974 through December 2010. Columbia, Missouri: OFFA. www.offa.org
• OFFA Health Surveys Divers. www.offa.org
• Kijas JW, Miller BJ, Pearce-Kelling SE, Aguirre GD, Acland GM. (2003)Canine models of ocular disease: outcross breedings define a dominant disorder present in the english mastiff and bull mastiff dog breeds. J Hered. 94(1):27-30.
• Zangerl B, Wickström K, Slavik J, Lindauer SJ, Ahonen S, Schelling C, Lohi H, Guziewicz KE, Aguirre GD. Assessment of canine BEST1 variations identifies new mutations and establishes an independent bestrophinopathy model (cmr3). Mol Vis. 2010 Dec 16;
• Bavegems, V. (2006) Erfelijke hartaandoeningen bij de hond. Gent: Universiteit Gent, Diergeneeskunde.
• Buchanan JW (1992) Causes and prevalence of cardiovascular diseases. In: Kirk RW, Bonagura JD (eds.) Current Veterinary Therapy XI. Philadelphia, PA, pp. 647-655.
• Selvarajah GT, Kirpensteijn J, van Wolferen ME, Rao NA, Fieten H, Mol JA. (2009) Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times. Mol Cancer. 8:72.